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. 2000 May 23;97(12):6868–6873. doi: 10.1073/pnas.120172697

Figure 7.

Figure 7

Expression of IGF-I and IGFBP-3 mRNAs is not altered in null ALS mice. Total RNA (15 μg) from the liver and kidney of 10-week-old wild-type (+/+, lanes 1 and 2) and null (−/−, lanes 3 and 4) ALS mice were analyzed by Northern blotting using an IGF-I (Left) or IGFBP-3 (Right) probe. For each probe, signals were normalized to the signal obtained with the 18S riboprobe (shown in Fig. 2). Means ± SE (six mice per genotype) are presented relative to the signal obtained for the wild-type animal. Means did not differ at P < 0.05 using GLM.