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. Author manuscript; available in PMC: 2007 May 24.
Published in final edited form as: Appl Microbiol Biotechnol. 2006 Nov 28;74(2):263–272. doi: 10.1007/s00253-006-0722-x

Figure 5. 3-OST-3a/PAP/tetrasaccharide complex.

Figure 5

A) crystal structure of 3OST-3A in complex with PAP(blue) and a tetrasaccharide HS molecule (green). B) Superposition of PAPS onto PAP in the active site of the 3OST-3a crystal structure. This figure displays the relative orientation of the acceptor 3-hydroxyl to the sufo group being transferred from PAPS. Side chains that are involved in binding the tetrasaccharide are shown. A sodium ion involved in binding is pictured in pink. The location of the kink, in the polysaccharide, is indicated by an arrow. C) Figure displaying side chain with specific functional groups of the bound tetrasaccharide. Hydrogen bonds are indicated by dashed lines.