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. Author manuscript; available in PMC: 2008 Jan 1.
Published in final edited form as: Pharmacogenomics. 2007 Jan;8(1):29–39. doi: 10.2217/14622416.8.1.29

Figure 1. Hypothetical structure of P-gp and corresponding SNP locations within the ABCB1 exonic region of the American population.

Figure 1

This figure illustrates the approximate locations of amino acid changes along the P-gp protein resulting from non-synonymous polymorphisms. A red “X” marks the approximate location of each polymorphism identified in this study. Black dots represent the approximate locations of common amino acid changes previously reported in the P-gp protein. Exons 1–28 are labeled by color and nucleotide length.