Figure 1.

Cell-based heat shock induction assay (HSIA). The materials tested were DMSO (negative control), geldanamycin (GDA, positive control), EtOAc extracts, and major fractions, radicicol (1) and monocillin (2), derived from C. chiversii and P. quadriseptata. All samples except F29 were tested at 5 μg/mL; the concentration of F29 used was 2.5 μg/mL. The mean and standard deviation (SD) of triplicate determinations are presented, expressed as a percentage of the negative control; results are representative of three independent experiments.