Table III.
Risk of ultrasound- or hysterectomy-confirmed uterine leiomyomata in relation to alcohol consumption in 1995: the Black Women’s Health Study, 1997–2001
| Person-years | Cases | Age-adjusted IRRa | Multivariate IRR (95% CI)b | |
|---|---|---|---|---|
| Alcohol consumption status | ||||
| Never drinker | 46 835 | 1319 | 1.00c | 1.00c |
| Former drinker | 8804 | 263 | 0.99 | 1.05 (0.91–1.20) |
| Current drinker | 17 786 | 595 | 1.12 | 1.13 (1.01–1.25) |
| Current alcohol consumption, drinks per week | ||||
| None | 55 639 | 1582 | 1.00c | 1.00c |
| 1–6 | 14 207 | 462 | 1.09 | 1.09 (0.98–1.21) |
| 7–13 | 2322 | 86 | 1.21 | 1.21 (0.97–1.51) |
| 14 + | 1257 | 47 | 1.22 | 1.23 (0.92–1.66) |
| Current alcohol consumption, grams per day | ||||
| None | 55 639 | 1582 | 1.00c | 1.00c |
| <5 | 7200 | 223 | 1.03 | 1.03 (0.90–1.19) |
| 5–14 | 7760 | 265 | 1.16 | 1.15 (1.00–1.31) |
| 15–24 | 1590 | 60 | 1.22 | 1.22 (0.94–1.59) |
| 25 + | 1236 | 47 | 1.24 | 1.25 (0.93–1.68) |
| Years of alcohol consumptiond | ||||
| Never drinker | 46 835 | 1319 | 1.00c | 1.00c |
| <10 years | 7034 | 189 | 1.00 | 1.03 (0.92–1.17) |
| 10–19 years | 7402 | 260 | 1.10 | 1.12 (0.98–1.27) |
| 20 + years | 3237 | 144 | 1.27 | 1.32 (1.11–1.58) |
| Type of alcohole | ||||
| Beer, drinks per week | ||||
| None | 55 639 | 1582 | 1.00c | 1.00c,e |
| <1 | 11 042 | 359 | 1.08 | 1.11 (0.98–1.27) |
| 1–6 | 5559 | 183 | 1.12 | 1.18 (1.00–1.40) |
| 7 + | 1185 | 53 | 1.44 | 1.57 (1.17–2.11) |
| Wine, drinks per week | ||||
| None | 55 639 | 1582 | 1.00c | 1.00c,e |
| <1 | 9520 | 329 | 1.15 | 1.16 (1.01–1.33) |
| 1–6 | 7657 | 244 | 1.07 | 1.05 (0.91–1.21) |
| 7 + | 609 | 22 | 1.19 | 1.15 (0.74–1.78) |
| Liquor, drinks per week | ||||
| None | 55 639 | 1582 | 1.00c | 1.00c,e |
| <1 | 11 587 | 378 | 1.08 | 1.08 (0.95–1.23) |
| 1–6 | 5441 | 194 | 1.21 | 1.18 (1.00–1.39) |
| 7 + | 758 | 23 | 1.00 | 0.95 (0.61–1.48) |
Adjusts for age at start of questionnaire cycle (1-year intervals) and time period (1997–1999 versus 1999–2001).
Adjusts for age, time period, age at menarche (years), parity (ever versus never), age at first birth (years), years since last birth (four knot restricted cubic spline), use of oral contraceptives (current, past, never), education (≤12, 13–15, 16, 17 + ), smoking (never, former, current), caffeine intake (ordinal) and BMI (kg/m2, four knot restricted cubic spline).
Reference group.
Omits two cases and 113 person-years among current drinkers with missing data.
Multivariate models further adjust for other sources of alcohol.