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. Author manuscript; available in PMC: 2008 Apr 5.
Published in final edited form as: Regul Pept. 2006 Dec 28;140(1-2):12–20. doi: 10.1016/j.regpep.2006.11.020

Figure 2.

Figure 2

Kallikrein treatment reduces cardiomyocyte apoptosis after acute MI. (A) Representative photomicrographs show TUNEL-positive apoptotic cardiomyocytes from the infarcted region of rat hearts. Original magnification is 200×. (B) Quantitative analysis of apoptotic cardiomyocytes expressed as percentage of TUNEL-positive nuclei in cardiomyocytes. TUNEL-positive non-cardiomyocytes were excluded. (C) NOx levels. (D) Representative Western blots of phosphorylated and total Akt and GSK-3β, and cleaved caspase-3. Values are expressed as mean ± SEM (n=6–7, *P<0.05 vs. MI & MI/TK+Icatibant).