Table 4.
Slopes and heritability coefficients for markers of bone metabolism in men and women
| Men | Women | |||
|---|---|---|---|---|
| Slope | H2 (%) | Slope | H2 (%) | |
| PTH | 1.31 ± 0.24 | 92* | 1.24 ± 0.32 | 85* |
| 25-OH vitamin D | 0.64 ± 0.18 | 82* | 0.67 ± 0.19 | 82* |
| 1,25-(OH)2 vitamin D | 0.66 ± 0.23 | 76* | 0.80 ± 0.16 | 90* |
| BSAP | 0.64 ± 0.28 | 68 | 0.39 ± 0.11 | 82* |
| Osteocalcin | 0.60 ± 0.21 | 77* | 0.65 ± 0.17 | 82* |
| DPD | 0.48 ± 0.11** | 88* | 1.03 ± 0.12 | 96* |
| NTX | 0.78 ± 0.11 | 94* | 0.75 ± 0.23 | 80* |
| PYD | 0.46 ± 0.34 | 49 | 1.06 ± 0.23 | 88* |
| Helical peptide | 0.77 ± 0.11 | 95* | 1.15 ± 0.52 | 78* |
| Urinary calcium | 0.96 ± 0.09 | 97* | 1.23 ± 0.25 | 89* |
Subjects were identical twins assigned at random to sedentary bed rest (CON) or bed rest combined with lower body negative pressure treadmill exercise (EX). Slope data are means ± SD for 8 subjects per group for all variables except osteocalcin, for which n = 6.
Heritability coefficients are statistically significant, P < 0.05.
Slopes for men and women are different, P < 0.05.