Table 1.
Main Clinical Data of the Patients
| Patient | Age/sex. onset of MF | Plaque lesions | Tumoral lesions | Status (June 99) | |||
|---|---|---|---|---|---|---|---|
| Date of sampling* | Previous treatment† | Onset of tumors | Date of sampling* | Previous treatment† | |||
| MF36 | 39/M 1993 | +36 (March-96) | Topical corticosteroids | 0 (March-93) | +36 (March-96) | Same | Alive, CR |
| MF39 | 67/M 1985 | +127 (April-96) | α-IFN | +118 (July-95) | +120 (Sept-95) | None | Alive t2NOMO |
| MF113 | 36/M 1984 | +168 (June-98) | Sunbathing Topical corticosteroids | +178 (April-99) | +180 (May-99) | Sunbathing, PUVA α-IFN | Alive T2N1MO |
| MF90 | 34/F 1986 | +36 (Sept 89) | None | +100 (July-94) | +130 (Oct-97) | PUVA, RePUVA, α-IFN, Electron-bean, C-MOPP, ABMT, Etoposide | Dead (lymphoma) |
| MF91 | 21/F 1973 | +288 (June 97) | Topical corticosteroids | +298 (March-98) | +298 (March-98) | Topical corticosteroids, PUVA | Alive T2N0M0 |
| MF73 | 43/M 1988 | +72 (Nov-94) | RePUVA α-IFN | +48 (Nov 92) | +48 (Nov 92) | BCNU | Aive T3N1M1 |
| Sunbathing, PUVA | |||||||
| MF78 | 27/M 1982 | +172 (July 96) | RePUVA, α-IFN RT (electrons) Topical mecloretamine, Photopheresis | +90 (Sept 89) | +184 (July 97) | Same | Alive T2N0M0 |
| MF82 | 66/F June-88 | +18 (Jan-90) | Sunbathing | +6 | +18 (Jan-90) | Same | Alive, CR |
| MF122 | 70/M 1995 | +6 (Feb 96) | Topical corticosteroids | 0 | 6+ (Feb 96) | Same | Dead (Oat-cell carcinoma) |
*Time from the onset of MF until molecular study was performed (months).
†Treatments performed before the date of sampling.
M, male; F, female; IFN, interferon; PUVA, photochemotherapy; RT, radiotherapy; ABMT, autologous bone marrow transplantation; T2, patches or plaques covering more than 10% of the body surface; T3, tumoral lesions; N0, no palpable lymph nodes; N1, palpable lymph nodes, histopathologically negative; M0, no visceral involvement; M1, visceral involvement; CR, complete remission.