Table 1.
Clinical and Demographic Characteristics, Pathologic Findings, Clonality, and EBV Detection for 17 Patients with Posttransplantation B-Cell Neoplasms
| Cases | Age | Sex | Organ transplanted | Graft-PT-LPD interval PT-LPDs | Morphology | Light chain | Clonality | EBV | |
|---|---|---|---|---|---|---|---|---|---|
| ISH | Southern | ||||||||
| 1 | 45 | M | Heart | 150 | Polymorphic | M | ND | + | ND |
| 2 | 50 | M | Heart | 90 | Polymorphic | M | ND | + | ND |
| 3 | 38 | F | Heart | 150 | Polymorphic | M | JHR | + | + |
| 4 | 68 | F | Heart | 210 | Polymorphic | M | JHR | + | + |
| 5 | 20 | M | Heart | 150 | Polymorphic | NM | ND | + | ND |
| 6 | 52 | M | Heart | 150 | Polymorphic | NM | GL | + | + |
| 7 | 51 | M | Lung | 180 | Polymorphic | NM | GL | + | + |
| 8 | 43 | M | Heart | 750 | Monomorphic | M | JHR | + | + |
| 9 | 56 | F | Kidney | 1200 | Monomorphic | M | ND | + | ND |
| 10 | 32 | M | Kidney | 450 | Monomorphic | M | JHR | + | + |
| 11 | 63 | M | Kidney | 680 | Monomorphic | M | JHR | + | + |
| 12 | 31 | M | Heart | 1660 | Monomorphic | M | JHR | + | + |
| 13 | 50 | F | Heart | 180 | Monomorphic | M | JHR | − | − |
| 14 | 43 | F | Liver | 900 | Monomorphic | M | JHR | − | − |
| 15 | 59 | M | Kidney | 3450 | Monomorphic | M | JHR | − | − |
| 16 | 57 | M | Kidney | 450 | Monomorphic | M | JHR | − | − |
| 17 | 56 | F | Kidney | 390 | Monomorphic | M | ND | − | − |
M, male; F, female; PT-LPD, posttransplantation lymphoproliferative disorders; M, monotypic light chain; NM, nonmonotypic; EBV, Epstein-Barr virus; ISH, in situ hybridization; ND, not done; Southern, Southern blot; JHR, rearrangement of Ig gene; GL, germline; +, positive; −, negative.