Table 4.
MI and AI of MG, CG1, CG2, CG5, and CG6 at Different Times after Transplantation
| 1 week | 3 weeks | 3 months | ||||
|---|---|---|---|---|---|---|
| Right part | Left part | Right part | Left part | Right part | Left part | |
| MI 1/1000 | ||||||
| MG | 0.55 ± 0.20¶ | 0.37 ± 0.10 | 9.50 ± 1.76*‡¶ | 0.39 ± 0.12 | 3.22 ± 1.09*§¶ | 0.04 ± 0.02‡§ |
| CG1 | 0.24 ± 0.09 | 0.16 ± 0.12‡ | 0.08 ± 0.07† | |||
| CG2 | 0.10 ± 0.09 | 0.31 ± 0.13 | 0.58 ± 0.21‡ | 0.17 ± 0.04 | 0.03 ± 0.03†§ | 0.06 ± 0.04 |
| CG5 | 0.25 ± 0.16 | 0.43 ± 0.21 | 0.37 ± 0.06‡¶ | 0.32 ± 0.13 | 0.36 ± 0.16† | 0.42 ± 0.09† |
| CG6 | 0.10 ± 0.06 | |||||
| AI 1/1000 | ||||||
| MG | 1.00 ± 0.27*¶ | 0.17 ± 0.05 | 2.05 ± 0,52*¶ | 0.10 ± 0.05 | 0.76 ± 0.19*§¶ | 0.04 ± 0.03 |
| CG1 | 0.14 ± 0.06† | 0.15 ± 0.06† | 0.03 ± 0.02† | |||
| CG2 | 1.22 ± 0.47* | 0.08 ± 0.02 | 0.21 ± 0.13† | 0.04 ± 0.03 | 0.02 ± 0.03†‡ | 0.04 ± 0.04 |
| CG5 | 0.38 ± 0.21 | 0.17 ± 0.05 | 0.35 ± 0.09†¶ | 0.25 ± 0.09 | 0.16 ± 0.04† | 0.16 ± 0.02† |
| CG6 | 0.03 ± 0.03 |
Shown are data of MI and AI at 1 week, 3 weeks, and 3 months after transplantation. Mean values ± SEM are shown. Each group consisted of six animals. MI is the number of mitotic figures of hepatocytes per 1000 hepatocytic nuclei. AI is the number of apoptotic bodies per 1000 hepatocytic nuclei. If more than 10,000 nuclei were counted, two digits after the digital point are given. MI and AI were separately calculated for the liver acini downstream of the transplanted ovarian fragments in the right part of the liver, and in the left part of the liver, which was free of transplants. When no alterations were identifiable downstream of the transplants, the indices for the right part of the liver were calculated with the hepatocytes in a distance of about 1 mm from the transplants. For CG1 and CG6, indices were only calculated for the right lobe.
* Significantly different from the left part of the liver.
† Significantly different from MG at the same time after transplantation.
‡ Significantly different from data at 1 week.
§ Significantly different from data at 3 weeks.
¶ Significantly different from CG6.
*†‡§/p Wilcoxon-Mann-Whitney test P < 0.05.