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. 2000 May;156(5):1797–1804. doi: 10.1016/S0002-9440(10)65051-1

Figure 1.

Figure 1.

Strain regulates MMP-1 expression by human monocytes/macrophages. Monocytes/macrophages were cultured on fibronectin-coated membranes for 4 to 5 days, fresh medium was exchanged, and cells were subjected to 4% mechanical strain at 1 Hz for 24 hours. Total RNA was isolated and analyzed by Northern blotting for MMP-1, MMP-3, and TIMP-1.