FIGURE 3. Distribution of nodal disease according to type. Nodal upstaging occurred in 10.7% (6/56) by evaluation of H&E stained step sections of SLNs alone in patients randomized to SLN mapping and targeted pathologic assessment. LN, lymph node; SLN, sentinel lymph node; H&E, hematoxylin & eosin; IHC, immunohistochemistry; FN, false-negative.