FIGURE 2. A, Creation of ischemic buttons to peritoneal sidewall as previously discribed (see reference 19). B, Adhesions to buttons at postoperative day 7. Reprinted from J Surg Res, 108 (1), Reed KL, Fruin AB, Bishop-Bartolomei KK, et al. Neurokinin-1 receptor and substance P messenger RNA levels increase during intraabdominal adhesion formation, pp 165–172, Copyright (2002) with permission from Elsevier.