Table 1.
Summary of phenotypic comparisons between arp1 and dhc mutants
| Process | Assays | Results |
|
|---|---|---|---|
| arp11/arp11 | dhc64C6-10/dhc64C6-10 | ||
| Cell cycle | Mitotic index and phenotype | Reduced mitotic index (decreased metaphase and prometaphase) | Altered mitotic distribution (increased metaphase, decreased prometaphase) |
| Abnormal mitotic figures | Abnormal mitotic figures | ||
| BrdU incorporation | Reduced incorporation | Reduced incorporation | |
| Disorganization of cycling cells | Disorganization of cycling cells | ||
| Somatic cell viability in mitotic clones | Complete lethality | Complete lethality | |
| Apoptosis | TUNEL | 35× increase | 6× increase |
| Oogenesis | Germline clones | 16 nurse cells and no oocyte (oocyte does not differentiate) | 16 nurse cells and no oocyte (oocyte does not differentiate) |
Methods and data supporting this table are in Supplemental Material.