FIGURE 4.
Sequence alignment for RPTPα-D1, RPTPμ-D1, and PTPηCD. The sequence of PTPηCD corresponds to the intracellular domain of the protein studied in current work (residues W875–A1216). The sequences of RPTPα-D1 and RPTPμ-D1 are of the polypeptide chains structurally defined in PDBs 1YFO and 1RPM, respectively. The residues at the dimerization interfaces are marked in gray (RPTPα-D1) and black (RPTPμ-D1). Residues in rPTPηCD amino acid sequence are gray when they match the correspondent residues of the RPTPα-D1 dimerization interface; they are black when identical to residues at the dimerization interface of RPTPμ-D1.