TABLE 2.

Literature values of diffusion coefficient (× 10⁻⁶ cm²/s) for various proteins of different MWs (× 10³) in water; all values corrected to 25°C using Dη/T = constant

Protein	D	MW
EGF (39)	1.34	6.6
IGF-I (35)	1.50*	7.6
cytochrome c (40)	1.33	13.4
RNase (33)	1.20	13.8
RNase (34)	1.27	13.8
RNase (20)	1.18	13.8
Lysozyme (41)	1.28	14.3
α-Lactalbumin (2)	1.21	14.2
Lactalbumin (40)	1.14	14.2
Trypsin (42)	1.25	15.1
Myoglobin (41)	1.18	16.9
Myoglobin (42)	1.29	16.9
α-Chymotrypsin (41)	1.17	21.6
Chymotrypsinogen (41)	1.09	21.6
Pepsin (43)	1.03	35.0
Ovalbumin (42)	0.78	43.5
Ovalbumin (40)	0.82	43.5
Ovalbumin (41)	0.83	43.5
BSA (40)	0.72	66.5
BSA (41)	0.64	66.5
BSA (44)	0.69	66.5
Fibrinogen (40)	0.34	339.7
Fibrinogen (42)	0.23	339.7

EGF, epidermal growth factor; BSA, bovine serum albumin.

^*Diffusion in proteoglycan-depleted cartilage.