Figure 7. Ureter Defects at UPJ and UVJ in Nfia Mutant Mice.

(A–C) Hematoxylin and eosin histology depicts duplication and dilatation of ureter at the UPJ in Nfia ^+/− (B, 60X) and Nfia ^−/− (C, 60X) newborn mice.

(D–F) Hematoxylin and eosin staining shows dilatation of UVJ in some Nfia ^+/− mutant mice (* in E, 60X); the majority of Nfia ^+/− and Nfia ^−/− mice show a normal UVJ (F, 60X).

a, abdominal aorta; bl, bladder; pe, pelvis; r, rectum; ur, ureter; UVJ, ureterovesical junction