Table 3. Conservation of ORFs (assigned orf number) among annotated baculovirus genomes.
| AcMNPV | Identity | BmMNPV | OpMNPV | LdMPV | SeMNPV | HaSNPV | HzSNPV | SpitMNPV | EppoMNPV | MacoNPV | RoMNPV | CuniNPV | BusuNPV | CpGV | PhopGV | XcGV | PxGV | Other baculoviruses |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ODV envelope proteins | ||||||||||||||||||
| 16 | BV/ODV-E26 | 8 | 15 | - | - | - | - | - | 13 | - | 14 | - | - | - | - | - | ||
| 22* | 44 kDa | 13 | 20 | 119 | 35 | 132 | 136 | 135 | 18 | 48 | 19 | 38 | 48 | 44 | 45 | 37 | CfMNPV, NeSeNPV | |
| 23* | f-protein | 14 | 21 | 130 | 8 | 133 | 137 | 136 | 19 | 9 | 20 | 104 | 31 | 27 | 27 | 26 | ||
| 46† | ODV-E66 | 37 | 50 | 131 | 57/114 | 96 | 99 | 98 | 42 | 78/144 | 43 | - | 37 | 33 | 149 | 30 | LsNPV, CfMNPV | |
| 80* | gp41 | 66 | 83 | 88 | 80 | 73 | 75 | 76 | 72 | 104 | 77 | 33 | 25 | 104 | 97 | 121 | 87 | AgMNPV, SfNPV |
| 83* | p96/vp91 | 69 | 86 | 91 | 77 | 76 | 78 | 79 | 75 | 101 | 80 | 35 | 101 | 94 | 118 | 84 | ||
| 94† | ODV-E25 | 77 | 95 | 96 | 71 | 82 | 85 | 85 | 82 | 94 | 91 | - | 91 | 83 | 99 | 74 | LsNPV, TnGV | |
| 138* | p74 | 115 | 134 | 27 | 131 | 20 | 19 | 21 | 121 | 160 | 131 | 74 | 60 | 55 | 77 | 49 | LsNPV, CfMNPV, TnNPV, SlNPV | |
| 143† | ODV-E18 | 119 | 140 | 19 | 136 | 10 | 10 | 12 | 125 | 166 | 135 | - | 44 | 14 | 12 | 12 | 13 | CfGV |
| 148* | ODV-E56 | 124 | 146 | 14 | 6 | 15 | 15 | 17 | 130 | 6 | 140 | 102 | 51 | 18 | 16 | 15 | 16 | CfMNPV, AsGV |
| Nucleocapsid and unassigned location proteins | ||||||||||||||||||
| 5 | 12.4 kDa | 134 | 7 | - | - | - | - | - | 5 | - | 3 | - | - | - | - | - | AfNPV | |
| 9 | p78/83 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 136 | - | 7 | - | - | 2 | 2 | - | AgMNPV, AfNPV | |
| 30 | 54.6 kDa | 21 | 38 | - | - | - | - | 30 | 30 | - | 27 | - | - | - | - | - | ||
| 39 | p43 | 30 | - | - | - | - | - | - | - | - | 36 | - | - | - | - | - | ||
| 49 | PCNA | - | 53 | - | - | - | - | - | - | - | 46 | - | - | - | - | - | ||
| 54* | vp 1054 | 43 | 58 | 57 | 105 | 47 | 48 | 49 | 49 | 133 | 52 | 8 | 34 | 138 | 126 | 175 | 115 | |
| 58 | 6.8 kDa | 47 | - | - | - | - | - | - | - | - | 56 | - | - | - | - | - | ||
| 59 | 8.2 kDa | 47 | 62 | 61 | 101 | 51 | 52 | 52 | - | - | 56 | - | 36 | - | - | - | - | LsNPV |
| 61† | FP25K | 49 | 64 | 63 | 98 | 53 | 54 | 57 | 55 | 125 | 58 | - | 39 | 118 | 110 | 140 | 100 | |
| 66 | 93 kDa | 54 | 71 | 82 | 92 | 66 | 68 | 68 | 59 | 114 | 63 | - | - | - | 133 | 94 | ||
| 70 | hcf-1 | - | - | - | - | - | - | - | - | - | 67 | - | - | - | - | 22 | ||
| 74 | 30.5 kDa | 60 | 77 | 135 | - | 68 | 70 | 71 | 66 | - | 71 | - | - | - | - | - | ||
| 77* | vlf-1 | 63 | 80 | 86 | 82 | 71 | 73 | 74 | 69 | 106 | 74 | 18 | 27 | 106 | 99 | 123 | 89 | AgMNPV |
| 79 | 12.1 kDa | 65 | 82 | - | - | - | - | - | 71 | - | 76 | - | 65 | - | 75 | - | AgMNPV | |
| 86 | PNK/PNL | - | - | - | - | - | - | - | - | - | 83 | - | - | - | - | - | ||
| 88 | cg30 | 71 | 89 | - | 76 | 77 | 80 | 80 | 76 | - | 85 | - | - | - | - | - | ||
| 89* | p39 | 72 | 90 | 92 | 75 | 78 | 81 | 81 | 77 | 99 | 86 | 24 | 96 | 88 | 111 | 79 | ||
| 92* | p33 | 75 | 93 | 94 | 73 | 80 | 83 | 83 | 80 | 96 | 89 | 14 | 93 | 85 | 101 | 76 | LsNPV | |
| 100* | p6.9 | 84 | 101 | 101 | 65 | 88 | 91 | 90 | 87 | 86 | 96 | 23 | 86 | 78 | 94 | 67 | ||
| 101† | BV/ODV-C42 | 85 | 102 | 102 | 64 | 89 | 92 | 91 | 88 | 85 | 97 | - | 85 | 77 | 93 | 66 | ClGV | |
| 102 | 13.1 kDa | 86 | 103 | 103 | 63 | 90 | 93 | 92 | 89 | 84 | - | - | - | 92 | 64 | |||
| 104 | vp80/p87 | 88 | 105 | 105 | 61 | 92 | 95 | 94 | 91 | - | 100 | - | - | - | - | - | CfMNPV, LsNPV | |
| 109* | 44.8 kDa | 92 | 109 | 107 | 59 | 94 | 97 | 96 | 95 | 80 | 104 | 69 | 55 | 50 | 53 | 43 | LsNPV | |
| 114 | 49 kDa | 94 | 114 | - | - | - | - | - | - | - | 108 | - | - | - | - | - | ||
| 129 | p24 | 106 | 127 | - | 10 | 118 | 122 | 116 | 114 | - | 122 | - | 11 | 71 | 63 | 80 | 53 | CfMNPV, HcNPV |
| 132 | 25.1 kDa | 109 | 130 | - | - | - | - | - | 117 | - | 125 | - | - | - | - | - | CfMNPV | |
| 133* | alk exo | 110 | 131 | 157 | 41 | 114 | 117 | 109 | 118 | 54 | 126 | 54 | 125 | 114 | 145 | 106 | CfMNPV | |
| 142* | 49 kDa | 118 | 139 | 20 | 137 | 9 | 9 | 11 | 124 | 167 | 134 | 30 | 15 | 13 | 13 | 14 | CfGV | |
| 144* | ODV-EC27 | 120 | 141 | 18 | 135 | 11 | 11 | 13 | 126 | 165 | 136 | 32 | 45 | 97 | 89 | 112 | 80 | |
| Viral DNA replication proteins | ||||||||||||||||||
| 14* | lef1 | 6 | 13 | 123 | 14 | 124 | 128 | 129 | 11 | 35 | 12 | 45 | 3 | 74 | 66 | 82 | 55 | CfMNPV |
| 65* | DNA polymerase | 53 | 70 | 83 | 93 | 67 | 69 | 61 | 58 | 115 | 62 | 91 | yes | 111 | 103 | 132 | 93 | CfMNPV, SlNPV, MbNPV, OaNPV |
| 67† | lef3 | 55 | 72 | 81 | 91 | 65 | 67 | 67 | 60 | 113 | 64 | - | 113 | 105 | 134 | 95 | SlNPV | |
| 95* | Helicase | 78 | 96 | 97 | 70 | 84 | 87 | 866 | 73 | 93 | 92 | 89 | 24 | 90/126 | 82/113 | 98 | 72 | |
| 147† | IE1 | 123 | 145 | 15 | 132 | 14 | 14 | 16 | 129 | 162 | 139 | - | 46 | 7 | 6 | 9 | 10 | TnSNPV, CfMNPV, HcNPV |
Virus acronym description and complete reference list are provided in Appendix 2, which is published as supporting information on the PNAS web site.
*
ORF is conserved among all sequenced baculovirus genomes.
†
ORF is conserved among all genomes except CuniNPV.