Fig. 1.

Antigen-specific reactivity in irradiated sporozoite immunized volunteers protected or not protected against sporozoite challenge. PBMCs derived from volunteers immunized with irradiated P. falciparum sporozoites and either protected or not protected against challenge with infectious sporozoites were tested by IFN-γ ELISPOT assay against peptide pools from putative P. falciparum proteins, as described in the text. Data are presented as summed SFC of all responses that met predefined criteria of positivity.