. 2007 May 30;104(25):10619–10624. doi: 10.1073/pnas.0701421104

Table 1.

Histomorphometric analysis of proximal tibia cancellous bone

Groups	Mineralizing surface, %	Mineral apposition rate, μm/day	Bone formation rate/bone surface, μm²/μm per day	Osteoclast surface, %
Sham + vehicle	24.56 ± 1.15	1.26 ± 0.06	114.15 ± 9.9	5.10 ± 0.49
OVX + vehicle	30.45 ± 2.39^*	1.43 ± 0.08	163.61 ± 18.6^*	8.38 ± 0.67^*
OVX + EE	20.22 ± 1.40^#	1.03 ± 0.06^*^#	77.91 ± 9.8^#	4.55 ± 0.46^#
OVX + PF-431396 (10)	36.81 ± 2.09^*^#^†	1.77 ± 0.09^*^#^†	240.17 ± 20.3^*^#^†	7.83 ± 0.73^*^†
OVX + PF-431396 (30)	40.60 ± 1.77^*^#^†	1.96 ± 0.09^*^#^†	291.43 ± 19.1^*^#^†	6.13 ± 0.48^#

*, P < 0.05 vs. sham plus vehicle;

#, P < 0.05 vs. OVX plus vehicle;

†, P < 0.05 vs. EE.