Table 2.
Groups | Parameters | |||
| ||||
TBARS (nmol MDA/mg protein) | SOD (IU/mg protein) | CAT (nmol H2O2-consumed/min/mg protein) | GSH (μmol of phosphorus liberated/min/mg protein) | |
| ||||
I (Normal healthy control) | 0.469 + 0.046 | 3.92 + 0.075 | 4.80 + 0.089 | 56.26 + 2.860 |
II (STZ treated, i.e., pathogenic control) | 6.802 + 0.895* | 0.162 + 0.030* | 0.323 + 0.010* | 17.35 + 5.020 |
III (STZ ± ER-100 mg/kg) | 3.78 + 0.833 # | 3.937 + 0.263 # | 2.767 + 0.770 | 34.20 + 3.500 @ |
IV (STZ ± ER-200 mg/kg) | 0.488 + 0.065 # | 2.236 + 0.066 # | 4.67 + 0.901 # | 39.20 + 1.070 # |
V (STZ ± gliclazide-25 mg/kg) | 2.159 + 0.401 # | 3.62 + 0.475 # | 4.66 + 1.320 # | 46.1 + 2.400 # |
*P < .01, as compared to group I (ANOVA followed by Dunnett's t test).
# P < .01, as compared to group II (ANOVA followed by Dunnett's t test).
@ P < .05, as compared to group I (ANOVA followed by Dunnett's t test).