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. Author manuscript; available in PMC: 2007 May 30.
Published in final edited form as: Nature. 2005 Oct 27;437(7063):1299–1320. doi: 10.1038/nature04226

Figure 7. Genealogical relationships among haplotypes and r2 values in a region without obligate recombination events.

Figure 7

The region of chromosome 2 (234,876,004–234,884,481 bp; NCBI build 34) within ENr131.2q37 contains 36 SNPs, with zero obligate recombination events in the CEU samples. The left part of the plot shows the seven different haplotypes observed over this region (alleles are indicated only at SNPs), with their respective counts in the data. Underneath each of these haplotypes is a binary representation of the same data, with coloured circles at SNP positions where a haplotype has the less common allele at that site. Groups of SNPs all captured by a single tag SNP (with r2 ≥ 0.8) using a pairwise tagging algorithm53,54 have the same colour. Seven tag SNPs corresponding to the seven different colours capture all the SNPs in this region. On the right these SNPs are mapped to the genealogical tree relating the seven haplotypes for the data in this region.