Determination of the amounts of fibronectin and LIF fragments in PCR
cDNA libraries. Relative amount of fibronectin and LIF fragments in PCR
libraries was determined by comparison of the signal intensity of
fibronectin and LIF in specified cDNA libraries
(Dpn-sLib and EcoR-sLib) with the signal
intensity of defined amounts of the cDNA fragments by Southern blot
hybridization. Lane 1, 100 ng of PCR-cDNA library from untreated cells;
lane 2, 100 ng of PCR-cDNA library from IFN-β + MEZ treated cells;
lanes 3 to 7, increasing amounts of cDNA fragments of fibronectin and
LIF (0.001, 0.01, 0.1, 1, and 10 ng, respectively). PhosphorImager
(Molecular Dynamics) scanning determined hybridized signal intensity.