Table 1.
Clones isolated with RaSH with the restriction enzyme DpnII
| Nomenclature* | Identity† | Mda type‡ |
|---|---|---|
| mda-D-25 | HLA cw6 | Type I |
| mda-D-26 | Novel, human homolog of Mus musculus small GTP-binding protein | Type I |
| mda-D-27, D-49, D-53, D-58, D-69 | Fibronectin | Type IV |
| mda-D-28 | Vascular endothelial growth factor (VEGF) (165) | Type IV |
| mda-D-33 | Cig5 (IFN-responsive RNA) | Type I |
| mda-D-34, D-36, D-46 | IL-11 | Type IV |
| mda-D-35 | Prolactin receptor-associated protein (PRA) | Type II |
| mda-D-39 | IL-1 | Type II |
| mda-D-40 | Plasminogen activator inhibitor type II | Type II |
| mda-D-41 | G-binding protein I | Type I |
| mda-D-42, D-54 | LIF | Type II |
| mda-D-45 | KIAA0439 from human brain | Type II |
| mda-D-48, D-52 | α5 integrin | Type II |
| mda-D-50 | Mac-2 binding protein 90 Kd product | Type I |
| mda-D-51, D-61 | Urokinase-type plasminogen activator receptor | Type II |
| mda-D-70 | Monocyte activation antigen | Type I |
| mda-D-55 | 2′-5′ oligoadenylate synthetase | Type I |
| mda-D-56 | Mn superoxide dismutase | Type III |
| mda-D-57, D-59, D-62 | 1-8U from the IFN-inducible gene family | Type I |
| mda-D-65 | ICAM-1 (intercellular adhesion molecule 1) | Type I |
| mda-D-68 | snRNP protein B | Type I |
| mda-D-32, D-47, D-63, D-66 | Novel | Type II |
*
Clones are designated as melanoma differentiation associated (mda) and the D designation refers to the fact that the restriction enzyme DpnII was used for isolation by the RaSH approach.
†
Sequences were searched against various DNA databases to determine sequence identities. Novel, no similar sequence reported in current DNA databases.
‡
Type I mda gene, inducible by IFN-β and IFN-β + MEZ; Type II mda gene, inducible by MEZ and IFN-β + MEZ; Type III mda gene, inducible by IFN-β, MEZ and IFN-β + MEZ; Type IV mda gene, inducible predominantly by IFN-β + MEZ.