Inhibition of the T cell proliferative responses to beryllium with mAbs
to class II MHC molecules. T cell lines from CBD patient 1 were
cultured with autologous LCL, 1 × 10-6 M
BeSO4, and increasing concentrations of anti-class II mAb.
Background proliferation without addition of BeSO4 was
6,262 ± 122, and stimulation to BeSO4 without
inhibitory antibodies was 25,574 ± 739 cpm. The data are
presented as percentage inhibition of stimulation as a function of the
concentration of anti-class II mAbs.