Table 2.
DP β-chain sequences of beryllium-presenting and nonpresenting alleles
| Ability to present Be | Amino acid position
|
|||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 7 | 8 | 9 | 11 | 17 | 33 | 35 | 36 | 55 | 56 | 57 | 65 | 68 | 69 | 76 | 84 | 85 | 86 | 87 | ||
| DPB1*0101 | Neg | Y | V | Y | G | A | E | Y | A | A | A | E | I | E | K | V | D | E | A | V |
| DPB1*0401 | Neg | – | L | F | – | – | – | F | – | – | – | – | – | – | – | M | G | G | P | M |
| DPB1*0201 | + | – | L | F | – | – | – | F | V | D | E | – | – | – | E | M | G | G | P | M |
| DPB1*0402 | + | – | L | F | – | – | – | F | V | D | E | – | – | – | – | M | G | G | P | M |
| DPB1*0601 | + | – | – | – | L | – | – | F | V | D | E | D | L | – | E | M | – | – | – | – |
| DPB1*1001 | + | – | – | H | L | – | – | F | V | D | E | – | – | – | E | – | – | – | – | – |
| DPB1*1701 | + | – | – | H | L | – | – | F | V | D | E | D | – | – | E | M | – | – | – | – |
Sequences for the different alleles are presented based on homology to DPB1*0101, and a dash indicates the same amino acid at that position. The bolded amino acid residues indicate charged sequence differences in presenting alleles compared to DPB1*0101.