Table 1.
Comparison of selected characteristics between online glucosamine trial and traditional clinic based clinical trials of osteoarthritis of the knee
|
Clinic based trials
|
|||||
|---|---|---|---|---|---|
| Characteristic | Online glucosamine trial | McKenna et al (2001)14 | Fransen et al (2001)13 | Baker et al (2001)12 | Pelletier et al (2000)11 |
| Sample size | 205 | 600 | 126 | 46 | 480 |
| Dropout rate (%) | 23.9 | 25.0 | 15.1 | 15.2 | 34.6 |
| Mean (SD) age | 60.2 (9.4) | 61.7* | 66.1 (10.3) | 68.5 (6) | 63.5 (8.9) |
| Mean (SD) body mass index | 32.6 (8.5) | NR | 29.4 (5.0) | 31.5 (4.5) | 31.3 (5.7) |
| Female (%) | 64.4 | 65.3 | 73.0 | 78.0 | 79.6 |
| Use of NSAIDs (%) | 79.5 | 77.8 | NR | 39.0 | NR |
| Mean (SD) WOMAC pain score | 44.5 (17.0)† | 53.4 (15.9) | 37.8 (19.5) | 40.9 (18.0) | NR |
| Mean (SD) WOMAC global score | 46.0 (16.7)† | 55.1 (15.2) | NR | NR | 73.6 (24.6) |
NR=not reported; NSAID=non-steroidal anti-inflammatory drug; WOMAC=Western Ontario and McMaster Universities osteoarthritis index.
*
No standard deviations reported.
†
Based on Likert scores transformed on to a 0-100 scale.