Table 1.

Clinical details and concurrent medications of the Type I and obese Type II diabetics (mean ± s.d.).

	Healthy	Type I	Obese Type II
n	10	14	8
Sex (M/F)	6/4	8/6	5/3
Race	6 Caucasian	11 Caucasian	4 Caucasian
	2 Hispanic, 2 Asian	3 African-American	4 African-American
Age (years)	32 ± 4	33 ± 8	46 ± 9*
Weight (kg)	74.1 ± 10.5	77.2 ± 12.3	106.6 ± 17.6*
BMI	26.6 ± 3.5	25.9 ± 3.9	37.5 ± 6.4*
Fasting glucose (mg dL−1)	83 ± 10	173 ± 114	199 ± 143
Cholesterol (mg dL−1)	160 ± 31	182 ± 39	219 ± 57*
HbA1c†††	nd†	9.3 ± 2.8	7.6 ± 3.5
		Concurrent medication
Drug category	Healthy	Type I	Obese Type II
Antidiabetic agents
Insulin	n.a.‡	14	4
Other§	n.a.		3
Renin angiotensin antagonists¶	n.a.	4	3
Antihyperlipidaemic**	n.a.	1	1
Diuretic††	n.a.		2
Hormones‡‡	n.a.	1	2
Antihypertensive§§	n.a.		2
Antidepressant¶¶	n.a.	1	1
Miscellaneous***	n.a.	2	1

^*Significantly (P≤ 0.05) different to healthy volunteers by anova with Tukey's correction.

^†Not determined.

^‡Not applicable.

^§Metformin (2), glimepiride (2), and one obese type II diabetic volunteer was successfully controlling their diabetes with diet modification.

^¶Drugs taken include (no. of people) benazepril, captopril, enalapril, lisinopril, ramipril, irbesartan, losartan.

^**Gemfibrozil, atorvastatin.

^††Furosemide, hydrochlorthiazide/triamterene.

^‡‡Oestrogen, levothyroxine, methimazole.

^§§Clonidine, verapamil. Nefazadone, sertraline.

^***Aspirin, coumarin, oxycodone and montelukast.

^†††HbA1_c (glycosylated hemoglobin) normal range is 4.8–8.0%.