Skip to main content
. 2003 Jun;55(6):544–551. doi: 10.1046/j.1365-2125.2003.01778.x

Table 1.

Details of the two studies included in the analysis.

Study 1* Study 2
Patient group Stable CHF Stable and unstable CHF
Study design Randomized, double blind, parallel group Randomized, double blind, parallel group
Study size 151 146§
Nominal sampling times 0, 0.5, 1, 2, 4, 8, 24, 24.5, 25, 26 0, 1, 2, 3, 4, 6, 24, 24.5, 25, 26, 28, 30, 48, 50/52**, 54
Bolus dose (µg kg−1) 3, 6, 12, 24, 36 6
Infusion rates (µg.kg min−1) 0.05, 0.1, 0.2, 0.4, 0.6 0.1, 0.2, 0.3, 0.4
Infusion durations (h) 24 6-48
*

See reference [14].

See reference [15].

Levosimendan, 95; placebo, 36; dobutamine, 20.

§

Levosimendan, 98; placebo, 48.

Hours after the start of the first infusion.

**

Sampling time depends on randomization code; even number = 50, odd number = 52.