Table 5.
Parameter | Estimate (% R.SE*) |
---|---|
Structural model parameters | |
CL (L h−1) | 13.3† (3.2) |
Bodyweight on CL (% kg−1) | 1.5 (20) |
V1 (l) | 16.8† (4.7) |
Bodyweight on V1 (% kg−1) | 0.9 (26) |
Q (l h−1) | 2.3 (12) |
V2 (l) | 30.0 (20) |
Variability parameters | |
CL (%) | 39 (14‡) |
Correlation CL-V1 | 0.47 (23§) |
Correlation CL-Q | 0.25 (47§) |
V1 (%) | 60 (18‡) |
Correlation V1-Q | −0.4 (40§) |
Q (%) | 170 (30‡) |
V2 (%) | 260 (43‡) |
Residual error (%) | 25 (7.8‡) |
Relative standard error.
Patient weighing 76 kg.
The R.SE (%) for the corresponding variance term.
The R.SE (%) for the corresponding covariance term.