Table 5.
Allele frequencies of SULT1A1 in various ethnic groups.
Allele frequency | |||||
---|---|---|---|---|---|
Population | n | *Arg | *His | P vs. Egyptian | Reference |
Egyptians† | 200 | 0.865 | 0.135 | Present study | |
Caucasians | |||||
American‡ | 150 | 0.690 | 0.310 | <0.0001 | [14] |
American‡ | 245 | 0.670 | 0.330 | <0.0001 | [41] |
German† | 300 | 0.630 | 0.370 | <0.0001 | [21] |
British† | 106 | 0.680 | 0.320 | <0.0001 | [40] |
Scottish† | 187 | 0.680 | 0.320 | <0.0001 | [40] |
Asians | |||||
Chinese‡ | 290 | 0.914 | 0.080 | 0.0018 | [41] |
Africans | |||||
Nigerian† | 52 | 0.730 | 0.270 | 0.0031 | [40] |
African-Americans‡ | 70 | 0.710 | 0.290 | <0.0001 | [41] |
n, Number of subjects. (Differences in allele frequencies were measured using Fisher's exact test.)
These studies were designed to detect only SULT1A1*2, so carriers of *3 or *4 alleles may be scored as carriers of SULT1A1*1 or *2.
These studies were designed to detect either *2 and *3 or *2,*3and*4. For this table, the common allele SULT1A1*1 and the rare alleles *3 and *4 were combined with the allele SULT1A1*1 and assigned as *Arg.