Table 2. Summary of results of the final base model.
| Fixed effects parameters | |||||
| Clearance | CL (l h−1) | 27.1 (1.42) | |||
| Central volume of distribution | V2 (l) | 97.7 (12.6) | |||
| Absorption rate constant | Ka (h−1) | 2.27 (0.184) | |||
| Distributional clearance | Q (l h−1) | 25.7 (3.45) | |||
| Peripheral volume of distribution | V3 (l) | 206 (55.7) | |||
| Lag time | lag (h) | 0.145 (0.0201) | |||
| Between-subject variability (ΩB) | |||||
| ωCL | ωV2 | ωKa | ωV3 | ωlag | |
| ωCL | 0.0396 (0.0245) | ||||
| ωV2 | – | 0.309 (0.180) | |||
| ωKa | – | – | 0 | ||
| ωV3 | – | – | – | 2.27 (2.22) | |
| ωlag | – | – | – | – | 0 |
| Between-occasion variability (ΩW) | |||||
| ωCL | ωV2 | ωKa | ωV3 | ωlag | |
| ωCL | 0.0175 (0.013) | ||||
| ωV2 | – | 0.912 (0.267) | |||
| ωKa | – | – | 3.4 (0.701) | ||
| ωV3 | – | – | – | 0.26 (0.234) | |
| ωlag | – | – | – | – | 0.106 (0.364) |
| Residual unexplained variance | |||||
| σ12 (exp) | σ22 (add) | ||||
| σ12 | 0.123 (0.0759) | ||||
| σ22 | – | 0.57 (0.503) | |||
Standard errors shown in parentheses.