Table 3. Population pharmacokinetic parameters for ceftazidime obtained by nonlinear mixed effect modelling.
Population estimates | SE of estimates | Interindividual variability CV percentage | |
---|---|---|---|
Clearance (L/h) | 2.72 | 0.088 | 56.3 |
Distribution volume of central compartment (L/kg) | 0.28 | 0.021 | 13.2 |
k12 (h−1) | 0.06718 | 0.1362 | 87.2 |
k21 (h−1) | 0.001823 | 0.1292 | 82.7 |