Table 1.
Details of three patients with apparently outlying whole-blood : plasma clozapine ratios (no patient consumed alcohol or used illicit drugs).
| Age (years) | Sex | Ethnicity | Smoker | Other drugs | Clozapine dose (mg day−1) | Plasma clozapine (mg l−1) | Plasma nor- clozapine (mg l−1) | Blood clozapine (mg l−1) | Blood nor- clozapine (mg l−1) | Haematocrit |
|---|---|---|---|---|---|---|---|---|---|---|
| 36 | F | Caucasian | No | Fluoxetine | 275 | 1.56 | 0.41 | 0.60 | 0.43 | 0.42 |
| 35 | F | Caucasian | Yes | Paroxetine, sodium valproate | 650 | 1.85 | 0.54 | 0.72 | 0.77 | 0.43 |
| 41 | M | Afro-Caribbean | Yes | Nil | 1025 | 1.73 | 1.20 | 0.95 | 1.36 | 0.44 |