Table 1.
Information regarding the demographic and biological characteristics (median (range)) of the population enrolled in the study.
| Covariates | Cycle 1 | Cycle 2 |
|---|---|---|
| Number of patients | 43 | 35 |
| Gender | Male 13, female 30 | Male 11, female 24 |
| Smoking status | Smoker 13, nonsmoker 30 | Smoker 12, nonsmoker 23 |
| Age (years) | 59 (29–77) | 61 (29–77) |
| Serum albumin concentration (g l−1) | 41 (26–50) | 40 (26–46) |
| Alkaline phosphatase (U l−1) | 152 (53–1320) | 185 (61–740) |
| Alanine amino transaminase (U l−1) | 17 (7–107) | 23 (8–157) |
| Aspartate amino transaminase (U l−1) | 24 (11–85) | 24 (13–74) |
| Total bilirubin (µmol l−1) | 7 (1–14) | 6 (2–12) |
| Body mass index (kg m−2) | 23.66 (16.65–35.21) | 23.26 (16.55–32.34) |
| Body surface area (m2) | 1.74 (1.38–2.3) | 1.71 (1.7–2.29) |
| Creatinine clearance* (ml min−1) | 75.4 (33.54–148.65) | 79.4 (34.9–225) |
| Height (cm) | 166 (148–197) | 166 (148–197) |
| Phosphate plasma concentration (mmol l−1) | 1.09 (0.59–1.45) | 1.05 (0.55–1.53) |
| Potassium plasma concentration (mEq l−1) | 4.3 (2.7–5.4) | 4.4 (2.9–5.3) |
| Plasma plasma protein (g l−1) | 72 (62–84) | 70 (61–84) |
| Serum creatinine concentration (µmol l−1) | 81 (48–125) | 77 (44–125) |
| Sodium plasma concentration (mEq l−1) | 140.0 (126–145) | 140 (130–154) |
| White blood cells counts (GI l−1) | 8.3 (3.9–41.2) | 6.3 (3.17–27.7) |
| Weight (kg) | 66.7 (45.1–96) | 66.7 (45.1–96) |
*
based on the Cockcroft & Gault equation X = 1.23 (male) and 1.04 (female).