Table 5.
Plasma distribution of tacrolimus in stable liver transplant recipients and those experiencing rejection
| Parameters | Stable (n = 25)*,† | Mild (n = 8)*,† | Moderate (n = 6)*,† | Severe (n = 1)#,† |
|---|---|---|---|---|
| Lipoprotein deficient serum fraction (%) | 54.6 | 53.3 | 54.7 | 50.2 |
| (52.1, 57.1) | (49.9, 56.7) | (47.4, 62.0) | ||
| High density lipoprotein fraction (%) | 29.2 | 30.1 | 30.0 | 30.3 |
| (50.4, 56.2) | (26.0, 34.2) | (24.9, 35.1) | ||
| Low density lipoprotein fraction (%) | 12.0 | 13.1 | 12.1 | 10.9 |
| (10.1, 13.9) | (11.6, 14.6) | (9.4, 14.8) | ||
| Very low density lipoprotein fraction (%) | 5.0 | 3.5 | 3.2 | 8.8 |
| (3.2, 6.8) | (2.5, 4.5) | (2.3, 4.1) |
*
Mean (95% confidence interval)
#
Mean (95% confidence interval not recorded due to low sample size)
†
Data are presented as percentage of total plasma concentration.