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The effects of intravenous methadone
| Placebo | Quinidine | 95% confidence interval | |
|---|---|---|---|
| tmax (h) | 0.3 ± 0.3 | 0.3 ± 0.2 | (−0.17, 0.22) |
| Peak miosis (mm) | 5.3 ± 0.8 | 5.1 ± 1.0 | (−0.39, 0.84) |
| AUC(0,8 h) (mm h) | 25.0 ± 5.7 | 26.8 ± 7.1 | (−6.1, 2.5) |
| kel (h−1) | 0.24 ± 0.14 | 0.17 ± 0.08 | (−0.019, 0.15) |
There were no significant differences between groups.
