Table 2. Comparative allele frequencies of TPMT in various populations.
Allele frequency | |||||||
---|---|---|---|---|---|---|---|
Populations | N | *1 | *2 | *3A | *3C | *6 | References |
Thai | 400 | 0.950 | 0 | 0 | 0.050 | 0 | Present study |
(0.924–0.969) | (0.031–0.076) | ||||||
Chinese | 384 | 0.977* | 0 | 0 | 0.023* | ND | [14] |
Japanese | 1044 | 0.984** | 0 | 0 | 0.016** | ND | [15] |
Japanese | 142 | 0.979** | 0 | 0 | 0.014 | 0.007 | [12] |
Taiwanese | 498 | 0.994** | 0 | 0 | 0.006** | 0 | [17] |
South-west Asians | 198 | 0.990** | 0 | 0.010* | 0* | ND | [14] |
South-east Asians | 600 | 0.990* | 0 | 0 | 0.010* | 0 | [17] |
Kenyans | 202 | 0.946 | 0 | 0 | 0.054 | ND | [25] |
Ghanaians | 434 | 0.924 | 0 | 0 | 0.076 | ND | [26] |
American Caucasians | 564 | 0.964 | 0.002 | 0.032* | 0.002** | ND | [22] |
British Caucasians | 398 | 0.947 | 0.005 | 0.045* | 0.003** | ND | [26] |
N represents number of alleles detected. Data in parentheses represent 95% CI. ND, not detected. Different from Thai population (
P < 0.05 and
P < 0.005).