Table 2. Absolute mean values for baselines by sequence with 95% CI for mean.
Baseline (first) | 95% CI | Baseline (second) | 95% CI | |
---|---|---|---|---|
NO (p.p.b) | 10.5 | 5.3, 15.6 | 9.0 | 3.9, 14.2 |
FEV1 (l) | 2.58 | 2.19, 2.97 | 2.59 | 2.20, 2.99 |
FEV1 (% predicted) | 84 | 77, 92 | 84 | 77, 92 |
FEF25–75 (l s−1) | 2.14 | 1.75, 2.54 | 2.18 | 1.78, 2.57 |
FEF25–75 (% predicted) | 58 | 49, 67 | 59 | 50, 68 |
Methacholine PC20 (mg ml−1) | 0.7 | 0.4, 1.2 | 0.6 | 0.4, 1.1 |
PEF (am) (l min−1) | 474 | 429, 518 | 466 | 421, 510 |
PEF (pm) (l min−1) | 475 | 433, 518 | 470 | 428, 513 |
Asthma symptom score (am) | 0.1 | −0.1, 0.3 | 0.2 | 0.1, 0.3 |
Asthma symptom score (pm) | 0.3 | 0.1, 0.5 | 0.3 | 0.1, 0.5 |
Rescue (am) (puffs/day) | 0.1 | −0.1, 0.3 | 0.2 | 0.1, 0.5 |
Rescue (pm) (puffs/day) | 0.4 | 0.1, 0.7 | 0.4 | 0.1, 0.7 |
Activities (MiniAQLQ) | 6.51 | 6.27, 6.75 | 6.63 | 6.39, 6.87 |
Symptoms (MiniAQLQ) | 5.93 | 5.50, 6.35 | 5.91 | 5.48, 6.33 |
Emotions (MiniAQLQ) | 6.30 | 5.83, 6.77 | 6.25 | 5.78, 6.71 |
Environment (MiniAQLQ) | 5.84 | 5.35, 6.33 | 6.05 | 5.56, 6.54 |
Overall (MiniAQLQ) | 6.14 | 5.81, 6.47 | 6.20 | 5.87, 6.52 |
There were no significant differences for comparisons between baselines in sequence irrespective of randomized treatments. Data for methacholine PC20are given in geometric means.