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CYP2D6 metabolic ratios (metoprolol/a-hydroxy-metoprolol) obtained following the administration of metoprolol in various drug combinations (alone: metoprolol only 4 drug: metoprolol, caffeine, chlorzoxazone and dapsone; 5 drug: metoprolol, caffeine,chlorzoxazone, dapsone and tolbutamide). EMs-Individual values (•), PMs-Individual values (▵), EMs (Mean ± SD) (
), PMs (Mean ± SD) (
)
