Table 2.
Pregnancy outcome for women exposed to amoxycillin/clavulanic acid (A/C) compared with that of women exposed to amoxycillin
| Pregnancy outcome | A/C | Amoxycillin | P | RR | 95% CI |
|---|---|---|---|---|---|
| Live births | 158/191 | 162/191 | 0.67 | 0.98 | 0.89, 1.07 |
| Stillbirth | 1/191 | 0/191 | 0.31 | ||
| Spontaneous abortion | 14/191 | 12/191 | 0.68 | 1.17 | 0.55, 2.46 |
| Induced abortion | 18/191 | 16/191 | 0.71 | 1.13 | 0.59, 2.14 |
| Gestational age at birth | 39.4 ± 1.6 (34–42) | 39.6 ± 1.6 (30–42) | 0.294* | ||
| Prematurity (<37 weeks) | 6/158 | 5/163 | 0.73 | 1.24 | 0.39, 3.97 |
| Birth weight (g) | 3239 ± 488 (1670–4300) | 3232.8 ± 468 (1950–4500) | 0.582* | ||
| Birth weight <2500 g | 7/158 | 6/163 | 0.75 | 1.2 | 0.41, 3.5 |
| Fetal distress | 5/158 | 5/163 | 0.97 | 1.03 | 0.3, 3.49 |
| Vaginal delivery | 126/158 | 142/163 | 0.04 | 0.92 | 0.83, 1.01 |
| Caesarean section | 33/158 | 20/163 | 0.04 | 1.7 | 1.02, 2.84 |
| Major malformations | 3/158 | 5/163 | 0.49 | 0.62 | 0.15, 2.55 |
*
T-test.