Table 2. Least squares mean values and ratios of the main pharmacokinetic parameters for miconazole.
| Treatment | Cmax (µg ml–1) | AUC(0,24 h) (µg ml–1 h) | AUC(0,12 h) (µg ml–1 h) | |
|---|---|---|---|---|
| 100 mg tablet | 19.4 | 76.0 | 45.6 | |
| 50 mg tablet | LS Means | 8.8 | 38.6 | 30.1 |
| Gel | 1.1 | 2.0 | 1.9 | |
| 100vs 50 | 2.2 | 2.0 | 1.5 | |
| (1.5, 3.2) | (1.2, 3.2) | (1.2, 3.2) | ||
| 100 vs gel | Ratio* | 17.2 | 37.2 | 24.2 |
| (90% CI*) | (11.8, 25.2) | (22.9, 60.5) | (22.9, 60.5) | |
| 50 vs gel | 7.8 | 18.9 | 16.0 | |
| (5.3, 11.4) | (11.7, 30.5) | (11.7, 30.5) |
obtained from Estimate statement of Proc GLM.