Table 1.

Table for the determination of initial dose of gentamicin (‘First Dose Table’); adapted from Begg and colleagues [4, 7, 11]

CLCr (ml min−1)	Initial dose (mg kg−1)	Target AUC (mg l−1 h)	Maximum daily dose (mg)
>66	5–7	70–100	560
54–66	5–6	85–100	480
42–54	5	100	400
30–42	4	100	320
21–30	3	100	240
<21	Seek specialist advice