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. 2004 Dec;58(6):648–664. doi: 10.1111/j.1365-2125.2004.02220.x

Table 2.

Problems identified in medication review reports and recommendations of medication changes based on medication reviews and primary healthcare team discussions

Problems identified in medication review reports % of problems N = 602
Condition caused by adverse drug reaction 16.9%
Sub-optimal monitoring 16.3%
Label discrepancy/other adherence difficulties, e.g. drug not taken as indicated by label or in patient profile (apparent non-concordance), under or overuse reported by patient, administration aid or device not effective 12.8%
Disorder treated with wrong (or suboptimal) drug 9.3%
Over- or subtherapeutic dosage of correct drug 9.3%
Condition caused by drug–drug, drug–food, drug–laboratory test interaction 9.1%
Other 7.8%
Untreated indication 6.3%
Sub-optimal drug administration 3.8%
Drug use without valid medical indication 3.5%
Poor medication knowledge 1.7%
Medication hoarding or poor storage of medication 2.5%
Problem associated with drug supply 0.5%
No problem stated 0.2%

Actions suggested following medication reviews and primary health care team discussions % of actions suggested N = 747

Monitoring – laboratory 21.0%
Change drug – substitute one drug for another 12.6%
Other, e.g. resolve non-concordance between patient-reported and GP-recorded drug regimen (4.4% of N); further investigation of potential ADE (1.6% of N) 11.9%
Provision of patient (or carer) education or information 10.4%
Cease drug or trial withdrawal to confirm need for treatment 9.5%
Change dose, dosage interval or frequency 8.7%
Add a drug 6.4%
No recommendation made 6.4%
Monitoring observation and non-lab monitoring 5.0%
Change administration time, route or dose form 3.5%
Rationalize medications held in the home 1.7%
Non-drug therapy suggested 1.5%
Other intervention to improve adherence 0.8%
Refer patient to another professional 0.5%

Feedback for 110 patients. Note there are more recommendations than problems, because the reviewing pharmacist sometimes suggested a range of possible interventions.