Figure 5. Downregulation of VCAM-1 and ICAM-1 by recombinant aPC in TNF-α–inflamed HIMECs.

HIMEC monolayers were left untreated or stimulated with TNF-α in the presence or absence of recombinant human aPC. After 24 hours, cells were suspended and VCAM-1 and ICAM-1 expression was measured by flow cytometry. Filled curve represents background signal from the isotype control. Values are representative of 5 separate experiments. Numbers represent the net percentage of positive cells.