Table 2.

Patient demographic distribution between groups on none, one, two and three target drugs

Number of target drugs	None	One	Two	Three
n (301)	135	87	60	19
Percent males	50	40	52	58
Age, mean ± SD	58 ± 21	70 ± 17*	74 ± 14*	82 ± 12*
Range	19–100	26–96	26–96	50–95
Number of diagnoses	2	4*	4*	5*
Previous renal failure diagnosed	9	12	6	6
Creatinine (mmol l−1), mean ± SD	0.09 ± 0.11	0.10 ± 0.06	0.11 ± 0.08	0.16 ± 0.08*
Median creatinine (mmol l−1)	0.07	0.08	0.09	0.14
Weight reading available	119	84	55	18
Mean weight ± SE, kg	68 ± 14	65 ± 13	68 ± 15	66 ± 8
Range	40–120	42–99	40–109	50–80
Creatinine clearance (ml s−1) ± SE	1.39 ± 0.65	1.04 ± 0.55**	0.93 ± 0.46**	0.53 ± 0.24**
Median creatinine clearance (ml s−1)	1.29	0.89	0.90	0.58

Creatinine and creatinine clearance levels:

^*P < 0.01;

^**P < 0.001.