Table 4.

Mean change in pulmonary function tests detecting significant effects after ipratropium bromide 10 µg

	Mean (95% CI) difference	P-value
(a) Healthy subjects
R5	14.9% (6.9–22.8)	0.004
R20	12.4% (3.5–21.3)	0.020
FEV1	2.0% (0.49–3.4)	0.024
(b) Mild asthma
sGaw 3	26.4 (11.2–41.6)	0.006
sGaw 10/6	22.8 (10.3–35.3)	0.004
MMEF	15.4 (5.7–25.2)	0.010
R5	8.4 (2.3–14.4)	0.020
FEV1	4.8 (1.3–8.4)	0.021
RF	8.0 (1.3–14.8)	0.040

Mean percentage difference (95% CI) refers to the difference between within day variability and changes after 10 µg of ipratropium bromide.