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Changes in INR over time in patients receiving placebo or paracetamol (4 g per day).
# paracetamol therapy was stopped in 3 patients because of 2 consecutive INR measurements above 3.5. There was no treatment interruption during the placebo period. Mean INR ± SD. *p < 0.05, INRji versus INRj0. Placebo n = 11 (○), paracétamol* (□)
