Table 4.
Spearman correlation coefficients and P-values showing the parameters that were significantly related to the free fractions of mycophenolic acid or mycophenolic acid glucuronide in 42 patients
| Free fraction | ||||
|---|---|---|---|---|
| Mycophenolic acid | Mycophenolic acid glucuronide | |||
| Parameter | Correlation | P-value | Correlation | P-value |
| Creatinine | 0.46 | 0.002 | 0.41 | 0.008 |
| Urea | 0.53 | <0.0001 | 0.41 | 0.007 |
| Albumin | −0.54 | <0.0001 | −0.31 | 0.049 |
| Total mycophenolic acid glucuronide AUC0−6 | 0.51 | <0.0001 | – | – |
| Free mycophenolic acid glucuronide AUC0−6 | 0.60 | <0.0001 | – | – |
Results were calculated using Spearman correlation tests. AUC0−6, Area under the curve from 0 to 6 h.