Table 2.

Combined genotypes of β₁AR and the risk for heart failure

β1Ser49Gly	β1Arg389Gly	Controls	Patients with heart failure	Odds ratio for heart failure (95%CI)	P-value
		No. of subjects
		119	91
≧ 1Gly	≧ 1Gly	6	6	1.00	–
≧ 1Gly	Arg/Arg	30	19	0.63 (0.18–2.25)	0.35
Ser/Ser	≧ 1Gly	34	25	0.74 (0.21–2.55)	0.43
Ser/Ser	Arg/Arg	49	41	0.84 (0.25–2.79)	0.50

Subjects with at least one β₁Gly49 allele and at least one β₁Gly389 allele served as the reference group. Odds ratios and P-values between the reference group and each other group were determined by 2 ×2 χ² test. P-value < 0.017 (0.05/3) was considered to be significant.